Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Light-Responsive Surface Topographies Modulate Macrophage Immune Responses Through Dynamic Mechanical Cues.

Macromolecular bioscience·2026
Same author

Immunomodulatory topographies regulate myofibroblast differentiation and influence fibrous encapsulation of glaucoma drainage devices.

Bioactive materials·2026
Same author

In vitro assessment of antibacterial and biocompatibility properties of a poly-ε-lysine and hyaluronic acid contact-killing coating to prevent prosthetic joint infection.

PloS one·2026
Same author

Curved Magnetic Hydrogels for Understanding Cancer Initiation.

ACS applied materials & interfaces·2025
Same author

Towards predicting implant-induced fibrosis: A standardized network model of macrophage-fibroblast interactions.

Computational and structural biotechnology journal·2025
Same author

Biomimetic Model for Electromagnetic Modulation of Cardiovascular Cellular Interactions On-Chip.

ACS applied bio materials·2025
Same journal

A DLP-Printed 3D Bioceramplug Fabricated Using a Photocurable Negative Thermo-Responsive Bioceramic Slurry for Cranial Burr-Hole Repair.

ACS biomaterials science & engineering·2026
Same journal

A Microenvironment-Driven Peptide Nanoplatform Enhances Ferroptosis and Antiangiogenic Activity for Triple-Negative Breast Cancer Therapy.

ACS biomaterials science & engineering·2026
Same journal

A Dural Extracellular Matrix Hydrogel with Neural Stem Cells Improves Recovery from Traumatic Brain Injury in Mice.

ACS biomaterials science & engineering·2026
Same journal

Biomimetic 3D-Printed Resorbable Extracellular Matrix-Guided Bone Regeneration Membrane Based on a Gelatin Methacrylate/Alginate-Hydroxyapatite Composite for Maxillofacial Surgery.

ACS biomaterials science & engineering·2026
Same journal

Sequential Biofunctionalization of a Choline-Based Monomeric Ionic Liquid and Polymerized Ionic Liquid: A Route to Dual Anionic Drug Polymer Conjugates of Piperacillin-Tazobactam.

ACS biomaterials science & engineering·2026
Same journal

Retinoic Acid-Functionalized Chitosan Polycationic Conjugates for Integrated Melanoma Therapy and Antibacterial Infection Control.

ACS biomaterials science & engineering·2026
查看所有相关文章

相关实验视频

Updated: Jun 11, 2025

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
09:11

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Published on: February 13, 2016

9.8K

磁驱动的水凝表面用于调节巨细胞行为.

Lanhui Li1,2, Els Alsema2,3, Nick R M Beijer3

  • 1Biosensors and Devices Lab, Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600MB Eindhoven, The Netherlands.

ACS biomaterials science & engineering
|October 9, 2024
PubMed
概括
此摘要是机器生成的。

磁激活的水凝 (MadSurface) 动态地改变了刚性,重新编程了巨细胞的表型. 这一突破为生物材料与宿主相互作用和可编程细胞行为调制提供了新的见解.

关键词:
动态硬度的变化改变了.磁性水凝是一种磁性水凝.调节的巨细胞极化脉冲磁场脉冲磁场是指一个脉冲的磁场.

更多相关视频

Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion
08:50

Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion

Published on: March 14, 2018

7.2K
Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release
08:39

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release

Published on: July 4, 2017

8.9K

相关实验视频

Last Updated: Jun 11, 2025

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
09:11

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release

Published on: February 13, 2016

9.8K
Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion
08:50

Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion

Published on: March 14, 2018

7.2K
Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release
08:39

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release

Published on: July 4, 2017

8.9K

科学领域:

  • 生物材料科学 生物材料科学
  • 细胞生物学 细胞生物学
  • 免疫学 免疫学 免疫学

背景情况:

  • 巨体在对生物材料微环境的反应中表现出动态的表型可塑性.
  • 开发控制这些微环境变化的工具对于研究宿主反应至关重要.
  • 目前的水凝基板对动态操纵和集成细胞培养/监测提出了挑战.

研究的目的:

  • 引入磁性驱动的水凝 (MadSurface) 进行动态和可逆的刚性控制.
  • 通过使用磁场和MadSurface来研究巨细胞行为的可编程调制.
  • 探索磁场,微环境变化和巨细胞表型变化之间的相互作用.

主要方法:

  • 用嵌入磁性微粒 (MadSurface) 制造的聚烯胺水凝.
  • 应用脉冲磁场 (0.1 Hz,50 mT) 来诱导可逆的刚性变化.
  • 使用流细胞计和ELISA分析巨细胞 (THP-1) 反应.

主要成果:

  • 通过脉冲磁场的动态刚度调节促进了M1-激活TPH-1细胞的亚群中向M2抗炎表型的转变.
  • 在单细胞水平上观察到CD206表达的增加,这表明M2极化.
  • 观察到的人口水平效应在研究的培养期内是有限的.

结论:

  • 麦德表面技术使得水凝基板的时间可控,可逆的刚性变化.
  • 这种方法为研究动态细胞微环境相互作用提供了一个新的平台.
  • 这些发现有助于进一步了解磁场和可调节的生物材料如何影响巨细胞的行为.