Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Cancer02:18

Cancer

51.7K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
51.7K
Tumor Progression02:07

Tumor Progression

6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.0K
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

7.6K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
7.6K
Cancer Survival Analysis01:21

Cancer Survival Analysis

863
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
863

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Light-Responsive Surface Topographies Modulate Macrophage Immune Responses Through Dynamic Mechanical Cues.

Macromolecular bioscience·2026
Same author

Biomimetic Model for Electromagnetic Modulation of Cardiovascular Cellular Interactions On-Chip.

ACS applied bio materials·2025
Same author

Mammalian cell culture and analysis in digital microfluidic platforms.

Lab on a chip·2025
Same author

Light-Responsive Liquid Crystal Surface Topographies for Dynamic Stimulation of Cells.

ACS applied materials & interfaces·2025
Same author

Long-term digital microfluidic chips for regulating macrophage cellular interactions in inflammation.

Lab on a chip·2025
Same author

Magnetically Driven Hydrogel Surfaces for Modulating Macrophage Behavior.

ACS biomaterials science & engineering·2024
Same journal

Removal of Codispersible Residual Impurities from CuInS<sub>2</sub>/ZnS Quantum Dots for Window-Replaceable Luminescent Solar Concentrators.

ACS applied materials & interfaces·2026
Same journal

Durable Core-Shell Scatterer Coating with Heat Storage for Radiative Cooling.

ACS applied materials & interfaces·2026
Same journal

Calix[6]arene-Based Interlocked Inverse Vulcanizate Enabling Network-Interface Cooperative Reinforcement in Natural Rubber/Carbon Black Composites.

ACS applied materials & interfaces·2026
Same journal

Resolving Thermal Accumulation and Rigid-Soft Interface Mismatch in Stretchable Electronics with Cubic Boron Nitride Composite Islands.

ACS applied materials & interfaces·2026
Same journal

Enhancing Conversion Reversibility and Initial Coulombic Efficiency of SnO<sub>2</sub> Anodes via NiO/Ni-Carbon Interfacial Design.

ACS applied materials & interfaces·2026
Same journal

Multidimensional Interface Structure Design for High-Efficiency Optically Controlled Semiconductor Devices: A Case Study on Memristive Synapses.

ACS applied materials & interfaces·2026
查看所有相关文章

相关实验视频

Updated: May 2, 2026

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release
08:39

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release

Published on: July 4, 2017

9.0K

曲线磁用于了解癌症的开始

Ana C Manjua1,2, Christian M Verkerk1, Burcu Gumuscu1,2,3

  • 1Biosensors and Devices Lab, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven 5600 MB, The Netherlands.

ACS applied materials & interfaces
|August 28, 2025
PubMed
概括
此摘要是机器生成的。

磁性水凝和低强度磁场改变癌细胞行为和基因表达,为研究癌症进展中的组织曲率提供了一个新工具. 这种方法显示了癌细胞对健康细胞的选择性.

关键词:
MDA-MB-231 乳腺癌细胞NHDF皮肤纤维细胞癌细胞的动态曲的脚手架磁纳米粒子磁性脚手架聚烯胺

更多相关视频

Preparation and Metabolic Assay of 3-dimensional Spheroid Co-cultures of Pancreatic Cancer Cells and Fibroblasts
10:51

Preparation and Metabolic Assay of 3-dimensional Spheroid Co-cultures of Pancreatic Cancer Cells and Fibroblasts

Published on: August 23, 2017

12.5K
Analysis of Cancer Cell Invasion and Anti-metastatic Drug Screening Using Hydrogel Micro-chamber Array HMCA-based Plates
08:32

Analysis of Cancer Cell Invasion and Anti-metastatic Drug Screening Using Hydrogel Micro-chamber Array HMCA-based Plates

Published on: October 25, 2018

9.2K

相关实验视频

Last Updated: May 2, 2026

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release
08:39

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release

Published on: July 4, 2017

9.0K
Preparation and Metabolic Assay of 3-dimensional Spheroid Co-cultures of Pancreatic Cancer Cells and Fibroblasts
10:51

Preparation and Metabolic Assay of 3-dimensional Spheroid Co-cultures of Pancreatic Cancer Cells and Fibroblasts

Published on: August 23, 2017

12.5K
Analysis of Cancer Cell Invasion and Anti-metastatic Drug Screening Using Hydrogel Micro-chamber Array HMCA-based Plates
08:32

Analysis of Cancer Cell Invasion and Anti-metastatic Drug Screening Using Hydrogel Micro-chamber Array HMCA-based Plates

Published on: October 25, 2018

9.2K

科学领域:

  • 生物材料科学
  • 癌症生物学
  • 细胞力学

背景情况:

  • 组织曲会影响癌细胞的动态, 但研究因工具不足而受到限制.
  • 了解曲组织如何推动癌症的进展对于开发新疗法至关重要.

研究的目的:

  • 使用磁性水凝研究动态组织曲率对转移性乳腺癌细胞的影响.
  • 在受控磁刺激下评估癌细胞表型和基因表达的变化.

主要方法:

  • 制造磁性烯胺水凝 (MACrylamide) 结构
  • 应用低强度 (100 mT) 的外部磁场来诱导动态曲率.
  • 在MACrylamide支架上培养MDA-MB-231乳腺癌细胞和NHDF纤维细胞.
  • 细胞面积,表型和基因表达的分析 (NMO1,OCT4,SOX4).

主要成果:

  • 磁刺激显著减少了癌细胞面积,从55%降至33%.
  • 磁和磁场改变了与抗炎反应,扩散和转移相关的基因表达.
  • 这种方法表现出选择性,对癌细胞的影响比健康纤维细胞更大.

结论:

  • 通过磁和磁场模拟的动态组织曲会影响癌细胞的行为和基因表达.
  • 这种生物相容的系统为研究曲组织环境中的癌症进展提供了一个新的工具.
  • 这些发现突显了动态曲率在致癌过程中的重要性,并提出了潜在的治疗途径.