在年轻成年人中,下丘脑连接和自我评估的攻击性
Yuxing Jared Yao1, Yu Chen2, Chiang-Shan R Li2,3,4
1Program in Neuroscience and Behavior, Wesleyan University, Middletown, CT 06459, U.S.A.
bioRxiv : the preprint server for biology
|October 14, 2024
概括
横向下丘脑 (LH) 的休息状态功能连接 (rsFC) 与人类的攻击性有关. 在LH-thalamus rsFC中观察到性别差异,这表明有明显的侵略神经通路.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 人类连接 漫画 人类连接
背景情况:
- 下丘脑对于包括侵略在内的有动机的行为至关重要.
- 之前的研究表明,中枢下丘脑 (MH) 和侧向下丘脑 (LH) 在侵略中起着不同的作用.
- 关于人体下丘脑静止状态功能连接 (rsFC) 和攻击性之间的关系的理解有限.
研究的目的:
- 调查LH和MH rsFC与大量年轻成年人群中的侵略之间的关联.
- 探索与侵略相关的RSFC模式中的潜在性别差异.
主要方法:
- 利用了745名年轻成年人的人类结合体项目 (HCP) 数据.
- 分析了LH和MH的rsFC,使用已建立的成像处理程序.
- 在攻击性得分上进行了rsFC的voxel-wise回归,并修正了统计值.
主要成果:
- 在LH和区域之间发现了显著的负 rsFC,包括中间状回,状回和状回 (在男性中),与侵略相关.
- 对于MH,没有观察到显著的rsFC.
- 证实了LH-thalamus rsFC与侵略之间的相关性中的性别差异.
结论:
- LH rsFC在人类的侵略中起作用.
- 在LH-thalamus rsFC中的性别差异与侵略有关.
- 对侵略性和相关心理健康特征的性别特异神经通路进行进一步的研究是有必要的.
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