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Updated: Jun 9, 2025

Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells
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Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells

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对检测染色体外圆形DNA的方法进行比较分析.

Xuyuan Gao1, Ke Liu1, Songwen Luo1

  • 1Department of Oncology, The First Affiliated Hospital of USTC, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Nature communications
|October 25, 2024
PubMed
概括

这项研究系统地评估了染色体外圆形DNA (eccDNA) 检测工具. Circle-Map和Circle_finder在短读分析方面表现出色,而CReSIL在长读eccDNA识别方面表现出色.

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DNA Isolation01:24

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DNA isolation protocols can be fast and straightforward or complex and time-consuming depending on the type and quality of DNA required for further processing. For example, plasmid DNA extraction is a bit more complicated than genomic DNA extraction because of the need for an appropriate lysis method to separate plasmid DNA from gDNA during isolation. However, for specific applications, such as long-range DNA sequencing that require a good yield of high- quality DNA samples, we need to follow...
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