多中心修改的Delphi练习,以确定用于分类早期症状膝关节关节炎的候选项目
L K King1, J W Liew2, A Mahmoudian3
1Department of Medicine, University of Toronto, Toronto, Canada.
Osteoarthritis and cartilage
|November 9, 2024
概括
研究人员通过专家共识确定了77个潜在项目,用于对早期症状膝关节关节炎 (EsSKOA) 进行分类. 这份清单将有助于区分EsSKOA和其他疾病和已确定的骨关节炎 (OA).
科学领域:
- 类风湿病学 类风湿病学
- 整形外科 整形外科 整形外科
- 临床流行病学 临床流行病学
背景情况:
- 早期症状膝关节骨关节炎 (EsSKOA) 需要精确的分类来进行有效的管理.
- 从临床上看,区分EsSKOA与已确定的骨关节炎 (OA) 和其他膝关节疾病是非常重要的.
- 目前还缺少EsSKOA分类的一组经过验证的项目.
研究的目的:
- 为了生成EsSKOA分类候选项的全面列表.
- 根据专家的共识和感知到的有用性来缩小这个列表.
- 为进一步基于数据的对分类项目的评估奠定基础.
主要方法:
- 进行了为期三轮的国际修改后的Delphi练习,涉及128名OA临床医生和研究人员.
- 参与者在9分级别上对108个候选项的有用性进行了评分.
- 如果物品的中位数是>5并且被至少33.3%的专家认为是有用的 (7-9),则被保留.
主要成果:
- 保留了77个候选项目,涵盖人口统计学,症状,体检,绩效测量,成像和实验室调查.
- 评分高的项目包括先前的膝关节损伤,在另一个关节诊断OA,以及与活动相关的膝关节疼痛.
- 项目实用性评级的四分之一区间最常为3,表明一些变化.
结论:
- 77个项目被OA专家确定为EsSKOA分类可能有用的项目.
- 该研究强调了专家们对特定项目的有用性存在的不确定性.
- 将采用更多数据驱动的方法来完善和缩小候选项目列表.
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Synarthrosis
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