Search research articles

关于 JoVE

概览领导团队博客 JoVE 帮助中心

作者

出版流程编辑委员会范围与政策同行评审常见问题投稿

图书馆员

用户评价订阅访问资源图书馆顾问委员会常见问题

研究

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments 存档

教育

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual 教师资源中心教师网站

使用条款与条件

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序

Same author

Messing with Signal 1: How Perturbed MHC Class I Antigen Presentation Contributes to Cancer.

Cells·2026

Same author

Phase Ib multicenter study of anti-TIM-3 (S095018/Sym023) in combination with anti-PD-1 (Sym021) in patients with advanced/metastatic recurrent biliary tract cancer.

Journal for immunotherapy of cancer·2026

Same author

Antibodies to watch in 2026.

mAbs·2026

Same author

Inhibition of A2AR alleviates adenosine-mediated suppression of plasma cell differentiation.

Frontiers in immunology·2025

Same author

Regulatory T Cells Poise the Myeloid Landscape after Chemotherapy in Lung Tumors.

Cancer immunology research·2025

Same author

The Sunrise of Tertiary Lymphoid Structures in Cancer.

Immunological reviews·2025

Search research articles

相关实验视频

Updated: Jun 7, 2025

Generation of Large Numbers of Myeloid Progenitors and Dendritic Cell Precursors from Murine Bone Marrow Using a Novel Cell Sorting Strategy

Generation of Large Numbers of Myeloid Progenitors and Dendritic Cell Precursors from Murine Bone Marrow Using a Novel Cell Sorting Strategy

Published on: August 10, 2018

在三级淋巴体结构内对免疫细胞群进行分类的方法开发.

Priyanka Devi-Marulkar^1,2,3,4, Hélène Kaplon^1,2,3,5, Marie-Caroline Dieu-Nosjean^6,7,8

¹Institut National de la Santé et de la Recherche Médicale (INSERM), UMRS 1138, Cordeliers Research Center, Laboratory "Cancer, Immune Control and Escape", Paris, France.

Methods in molecular biology (Clifton, N.J.)

|November 11, 2024

概括

在非小细胞肺癌 (NSCLC) 中研究瘤微环境揭示了免疫细胞的预后价值. 新的流细胞计法有助于分析NSCLC患者的调节性T细胞 (Treg),B细胞和玛-三角形 (γδ) T细胞.

关键词:

流动细胞计量流动细胞计量马三角形T细胞的细胞.肺癌是一种肺癌.监管T细胞监管T细胞三级淋巴体结构的第三级淋巴体结构.瘤免疫学瘤免疫学瘤微环境是一个微环境.瘤透的B细胞进入了瘤.

更多相关视频

Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning

Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning

Published on: November 19, 2018

Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays

Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays

Published on: June 9, 2015

相关实验视频

Last Updated: Jun 7, 2025

Generation of Large Numbers of Myeloid Progenitors and Dendritic Cell Precursors from Murine Bone Marrow Using a Novel Cell Sorting Strategy

Generation of Large Numbers of Myeloid Progenitors and Dendritic Cell Precursors from Murine Bone Marrow Using a Novel Cell Sorting Strategy

Published on: August 10, 2018

Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning

Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning

Published on: November 19, 2018

Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays

Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays

Published on: June 9, 2015

科学领域:

免疫学免疫学免疫学
在瘤学瘤学.
癌症研究癌症研究

背景情况:

瘤微环境 (TME) 对瘤进展和患者的治疗结果至关重要.
特定的免疫细胞种群,包括T-辅助型1 (Th1),记忆CD8+T细胞和三级淋巴体结构,与改善各种癌症的存活率有关.
固体瘤中调节性T细胞 (Treg),B细胞和玛-三角形 (γδ) T细胞的预后意义尚未完全理解.

研究的目的:

开发和应用基于流细胞计的新策略来隔离特定的免疫细胞群.
评估调节性T细胞 (Treg),B细胞和玛-三角形 (γδ) T细胞在非小细胞肺癌 (NSCLC) 中的预后作用.

主要方法:

利用先进的流动细胞测量技术进行细胞分类.
专注于隔离调节性T细胞 (Treg),B细胞和马-三角形 (γδ) T细胞.
将这些方法应用于非小细胞肺癌 (NSCLC) 患者的样本.

主要成果:

成功开发和实施了用于免疫细胞隔离的新型流细胞计策略.
生成数据,以促进对Treg,B细胞和γδ T细胞在NSCLC中的作用的评估.
为进一步分析它们的预后价值奠定了基础.

结论:

新的流式细胞计量方法可以在NSCLC瘤微环境中精确隔离免疫细胞.
这些技术对于剖析各种免疫群体的复杂作用至关重要,包括Treg,B细胞和γδ T细胞.
使用这些方法的进一步研究将澄清这些免疫细胞在NSCLC的预后影响,可能改善患者分层和治疗策略.