相关实验视频

Updated: May 7, 2025

Automated Production of Human Induced Pluripotent Stem Cell-Derived Cortical and Dopaminergic Neurons with Integrated Live-Cell Monitoring
09:34

Automated Production of Human Induced Pluripotent Stem Cell-Derived Cortical and Dopaminergic Neurons with Integrated Live-Cell Monitoring

Published on: August 6, 2020

7.1K

来自患者的诱导多能干细胞作为研究前性痴呆病理学的模型

Sonia Infante-Tadeo, Diane L Barber

    bioRxiv : the preprint server for biology
    |January 7, 2025
    PubMed
    概括

    前性痴呆症 (FTD) 患者的细胞在成为神经元之前表现出疾病症状. 溶酶体功能障碍是关键的,这些细胞可以模拟FTD和测试药物.

    更多相关视频

    In vitro Modeling for Neurological Diseases using Direct Conversion from Fibroblasts to Neuronal Progenitor Cells and Differentiation into Astrocytes11:42

    In vitro Modeling for Neurological Diseases using Direct Conversion from Fibroblasts to Neuronal Progenitor Cells and Differentiation into Astrocytes

    Published on: June 10, 2021

    4.8K
    A Guide to Generating and Using hiPSC Derived NPCs for the Study of Neurological Diseases09:30

    A Guide to Generating and Using hiPSC Derived NPCs for the Study of Neurological Diseases

    Published on: February 21, 2015

    18.2K

    相关概念视频

    EPS and iPS Cells in Disease Research01:21

    EPS and iPS Cells in Disease Research

    Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
    2.7K
    Induced Pluripotent Stem Cells01:13

    Induced Pluripotent Stem Cells

    Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
    21.6K
    iPS Cell Differentiation01:22

    iPS Cell Differentiation

    The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
    2.6K