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Updated: Jun 3, 2025

Long-term Time Lapse Imaging of Mouse Cochlear Explants
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Published on: November 2, 2014

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通过依赖乳酸的转录调节,PKM2控制着耳的发育

Mingxuan Wu1,2, Gaogan Jia1,2, Yaoqian Liu1,2

  • 1ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200031, China.

Proceedings of the National Academy of Sciences of the United States of America
|January 8, 2025
PubMed
概括

由酸盐激酶M2 (PKM2) 驱动的糖解质代谢对于内耳发育和毛细胞再生至关重要. PKM2活动和随后的乳酸盐生产在表观遗传学上调节了对感觉上皮质形成至关重要的基因表达.

关键词:
在PKM2中,PKM2是PKM2.发展发展发展发展发展.糖溶性新陈代谢的发生.头发细胞是指毛细胞.复兴再生是一种再生方式.

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