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相关概念视频

Accelerating Fluids01:17

Accelerating Fluids

When a fluid is in constant acceleration, the pressure and buoyant force equations are modified. Suppose a beaker is placed in an elevator accelerating upward with a constant acceleration, a. In the beaker, assume there is a thin cylinder of height h with an infinitesimal cross-sectional area, ΔS.
The motion of the liquid within this infinitesimal cylinder is considered to obtain the pressure difference. Three vertical forces act on this liquid:
Production of Formed Elements01:34

Production of Formed Elements

Hemangioblasts are multipotent stem cells originating from the mesoderm. They give rise to hematopoietic stem cells (HSCs), which undergo hematopoiesis to produce all the formed elements of blood. This process is regulated by a complex network of hematopoietic growth factors, including transcription factors, growth factors, and cytokines. These factors stimulate the HSCs to divide and differentiate, though some HSCs remain undifferentiated to maintain a self-renewing pool.
Most HSCs commit to...
Steady Flow of a Fluid Stream01:27

Steady Flow of a Fluid Stream

Consider a control volume, such as a pipe with solid boundaries, through which fluid flows and changes direction due to the impulse exerted by the resulting force from the pipe walls. In steady flow, the mass of fluid entering the control volume at a given time, t, with velocity v1, is equal to the mass leaving after infinitesimal time dt, with velocity v2.
During this process, the momentum of the fluid within the control volume remains constant over the time interval dt. By applying the...
Streamlines, Streaklines, and Pathlines01:18

Streamlines, Streaklines, and Pathlines

A streamline represents the trajectory that is always tangent to the fluid's velocity vector at any given point. The velocity of a fluid particle is always directed along the streamline, ensuring the particle continuously follows the streamline's path. Streamlines are particularly useful for visualizing the overall direction of flow in a fluid system, and they provide an instantaneous representation of the flow's velocity field. In steady flow, where conditions do not change over time,...
Design Example: Creating a Hydraulic Model of a Dam Spillway01:21

Design Example: Creating a Hydraulic Model of a Dam Spillway

Scaled hydraulic models of dam spillways provide a practical way to replicate and study the intricate flow dynamics of these structures. Often built to a 1:15 ratio, these models allow for observing critical water behavior, such as velocity distribution, flow patterns, and energy dissipation.
Laminar Flow01:27

Laminar Flow

Laminar flow represents a smooth, orderly fluid motion where particles move along parallel paths, resulting in minimal mixing between layers. Streamlined particle paths characterize this flow regime and occur under conditions where viscous forces dominate over inertial forces. The distinction between laminar, transitional, and turbulent flow is primarily determined by the Reynolds number, a dimensionless quantity calculated as:

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相关实验视频

Updated: Jun 20, 2026

A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules
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A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules

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组件库的创建和像素阵列的生成与微磨滴滴微流体.

David McIntyre1,2, Diana Arguijo1,2, Kaede Kawata2,3

  • 1Biomedical Engineering Department, Boston University, Boston, MA, USA.

Microsystems & nanoengineering
|January 14, 2025
PubMed
概括
此摘要是机器生成的。

我们开发了一种低成本的,用于液滴微流体装置的快速原型制造方法,在一天内实现了完整的设计-构建-测试周期. 这种方法为高通量生物和化学应用提供了一个多功能组件库.

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Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
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科学领域:

  • 微流体学 微流体学
  • 生物技术是生物技术.
  • 化学工程是化学工程的重要组成部分.

背景情况:

  • 滴滴微流体对于高通量选和配方至关重要.
  • 传统的聚二甲基 (PDMS) 装置制造是缓慢的,昂贵的,需要专门的设施.

研究的目的:

  • 为滴滴微流体器件展示一种新的,低成本的制造方法.
  • 创建一个基于滴滴的微流体组件的全面图书馆.
  • 为了展示微流体设备的快速设计-制造-测试周期.

主要方法:

  • 利用低成本的快速原型和电极集成用于设备制造.
  • 开发了离散的微流体组件,用于滴滴生成,再注入,皮可注入,定,传感和分类.
  • 将组件组装成滴滴"像素"阵列,用于成像应用.

主要成果:

  • 每个设备的制造成本低于12美元.
  • 在24小时内完成了完整的设计-建造-测试周期.
  • 已证明具有生物相容性,低成本和高通量的微流体组件.

结论:

  • 新的制造方法大大降低了滴滴微流体器件的成本和周转时间.
  • 开发的组件库支持复杂的,多步骤的工作流.
  • 这项技术使各种科学应用的液滴微流体获得民主化.