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相关概念视频

Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

8.7K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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Olfaction01:25

Olfaction

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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
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Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

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Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
7.9K
Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

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Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
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COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
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Prosopagnosia01:24

Prosopagnosia

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Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
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相关实验视频

Updated: May 31, 2025

Author Spotlight: Assessing the Olfactory Effects of Airborne Pollutants &#8212; Buried Food and Social Odor Tests
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Author Spotlight: Assessing the Olfactory Effects of Airborne Pollutants — Buried Food and Social Odor Tests

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持续的COVID-19后嗅觉功能障碍及其与自主神经系统功能的关联:一个案例对照研究.

Lojine Ayoub1,2, Abeer F Almarzouki2, Rajaa Al-Raddadi3

  • 1Department of Physiology, Faculty of Medicine, Rabigh Branch, King Abdulaziz University, Rabigh 21911, Saudi Arabia.

Diseases (Basel, Switzerland)
|January 24, 2025
PubMed
概括
此摘要是机器生成的。

后COVID-19患者经常经历嗅觉和味觉功能障碍,可能与自主性问题有关. 需要进一步的研究,以了解感染后持续的嗅觉和自主性问题.

关键词:
自主功能障碍的自主功能障碍.在COVID-19后的时间里.主观和客观的气味测试.

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Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders
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A Free-breathing fMRI Method to Study Human Olfactory Function
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Author Spotlight: Assessing the Olfactory Effects of Airborne Pollutants &#8212; Buried Food and Social Odor Tests
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Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders
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Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders

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A Free-breathing fMRI Method to Study Human Olfactory Function
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A Free-breathing fMRI Method to Study Human Olfactory Function

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科学领域:

  • 神经学 神经学
  • 耳鼻喉科 耳鼻喉科 耳鼻喉科
  • 传染性疾病 传染性疾病

背景情况:

  • 冠状病毒疾病2019 (COVID-19) 流行病导致许多患者报告持续的嗅觉和味觉功能障碍.
  • 嗅觉和味觉缺陷是COVID-19的常见后果,影响生活质量.

研究的目的:

  • 确定患有COVID-19病史的人群中嗅觉和味觉功能障碍的患病率.
  • 调查COVID-19后嗅觉/口味功能障碍,自主功能障碍和残疾之间的关联.

主要方法:

  • 一项病例控制研究比较了82名COVID-19患者和82名对照人群.
  • 嗅觉功能障碍 (包括鼻) 和口味问题通过自我报告和快速嗅觉识别测试 (QSIT) 进行了评估.
  • 使用复合自主症状尺度-31 (COMPASS-31) 评估自主功能.

主要成果:

  • 与对照组相比,COVID-19后组的嗅觉 (26.8%) 和味觉 (14.6%) 功能障碍显著增加.
  • 后COVID-19患者报告的气味 (36.6倍) 和味道 (8.22倍) 问题显著增加.
  • 机密运动功能障碍与异常的QSIT和帕罗斯米亚得分有显著的相关性,这表明自主和嗅觉功能障碍之间存在联系.

结论:

  • 自主功能障碍和COVID-19后持续的嗅觉缺陷之间存在潜在的关联.
  • 需要进一步的研究来澄清这些持续的COVID-19后症状背后的机制.