持续的COVID-19后嗅觉功能障碍及其与自主神经系统功能的关联:一个案例对照研究
Lojine Ayoub1,2, Abeer F Almarzouki2, Rajaa Al-Raddadi3
1Department of Physiology, Faculty of Medicine, Rabigh Branch, King Abdulaziz University, Rabigh 21911, Saudi Arabia.
Diseases (Basel, Switzerland)
|January 24, 2025
概括
后COVID-19患者经常经历嗅觉和味觉功能障碍,可能与自主性问题有关. 需要进一步的研究,以了解感染后持续的嗅觉和自主性问题.
科学领域:
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
背景情况:
- 冠状病毒疾病2019 (COVID-19) 流行病导致许多患者报告持续的嗅觉和味觉功能障碍.
- 嗅觉和味觉缺陷是COVID-19的常见后果,影响生活质量.
研究的目的:
- 确定患有COVID-19病史的人群中嗅觉和味觉功能障碍的患病率.
- 调查COVID-19后嗅觉/口味功能障碍,自主功能障碍和残疾之间的关联.
主要方法:
- 一项病例控制研究比较了82名COVID-19患者和82名对照人群.
- 嗅觉功能障碍 (包括鼻) 和口味问题通过自我报告和快速嗅觉识别测试 (QSIT) 进行了评估.
- 使用复合自主症状尺度-31 (COMPASS-31) 评估自主功能.
主要成果:
- 与对照组相比,COVID-19后组的嗅觉 (26.8%) 和味觉 (14.6%) 功能障碍显著增加.
- 后COVID-19患者报告的气味 (36.6倍) 和味道 (8.22倍) 问题显著增加.
- 机密运动功能障碍与异常的QSIT和帕罗斯米亚得分有显著的相关性,这表明自主和嗅觉功能障碍之间存在联系.
结论:
- 自主功能障碍和COVID-19后持续的嗅觉缺陷之间存在潜在的关联.
- 需要进一步的研究来澄清这些持续的COVID-19后症状背后的机制.
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