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Updated: Jun 24, 2026

Formulating and Characterizing Lipid Nanoparticles for Gene Delivery using a Microfluidic Mixing Platform
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Published on: February 25, 2021

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探索将不同生物活性脂物纳入信使核糖核酸脂质纳米粒子 (mRNA LNP) 配方的效果

Sunny P Chen1,2, Shuangyu Wang3, Suiyang Liao1,2,3

  • 1School of Biomedical Engineering, University of British Columbia, Vancouver V6T 1Z3, Canada.

ACS bio & med chem Au
|February 24, 2025
PubMed
概括

研究人员探索了将生物活性脂添加到脂质纳米粒子 (LNP) 配方中,用于RNA疗法. 这个第五个组件调节了LNP的特性和生物功能,扩大了有效药物输送的设计可能性.

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lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...