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Updated: May 16, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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基于PDFL的机器学习来预测蛋白质-连接物结合的亲和力

Mushal Zia1, Benjamin Jones1, Hongsong Feng1

  • 1Department of Mathematics, Michigan State University, East Lansing, Michigan 48824, United States.

Journal of chemical theory and computation
|April 5, 2025
PubMed
概括

我们介绍了一种新方法,持久定向旗拉普拉西安 (PDFL),用于分析生物分子网络中的定向相互作用. PDFL提高了蛋白质-联体结合亲和力的预测,有助于药物发现.

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