相关实验视频

Updated: May 10, 2025

3D Visualization of Retinal Vascular Pericytes in Mice by Immunostaining
09:22

3D Visualization of Retinal Vascular Pericytes in Mice by Immunostaining

Published on: November 1, 2024

415

LRG1改变了细胞的表型,并影响了血管成熟

Alexandra E Hoeh1, Jui-Hsien Chang1, Ronja S Mueller1

  • 1Institute of Ophthalmology, University College London, London EC1V 9EL, UK.

Cells
|April 25, 2025
PubMed
概括

富含白的α-2-糖蛋白-1 (LRG1) 损害了视网膜血管的发育,减少了细胞周围的覆盖和血管成熟. 这种血管病变因素突出显示了血管疾病潜在的LRG1阻断疗法.

关键词:
血管新生的产生.血管成熟 血管成熟血液视网膜屏障 视网膜屏障富含白蛋白的α-2-糖蛋白-1 (LRG1) 是一种细胞周围细胞.

更多相关视频

A Method for Labeling Vasculature in Embryonic Mice09:58

A Method for Labeling Vasculature in Embryonic Mice

Published on: October 7, 2011

15.5K
Retinal Cryo-sections, Whole-Mounts, and Hypotonic Isolated Vasculature Preparations for Immunohistochemical Visualization of Microvascular Pericytes10:46

Retinal Cryo-sections, Whole-Mounts, and Hypotonic Isolated Vasculature Preparations for Immunohistochemical Visualization of Microvascular Pericytes

Published on: October 7, 2018

9.9K

相关概念视频

Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
2.5K