在荷尔蒙避孕药的非计划性出血治疗选择
Lule Rault1, Shandhini Raidoo1
1Department of Obstetrics, Gynecology, and Women's Health, University of Hawaii John A. Burns School of Medicine, 1319 Punahou Street, Suite 824, Honolulu, HI 96826, USA.
概括
由于荷尔蒙避孕药的非预定的出血可以通过咨询和治疗,如NSAIDs或雌激素来管理. 新兴疗法在减少各种避孕药使用者的突破性出血方面表现有前途.
科学领域:
- 生殖健康 生殖健康
- 药理学 药理学是指药理学的学科.
背景情况:
- 无计划出血是荷尔蒙避孕药常见的副作用,经常导致使用者停止使用.
- 有效的管理策略对于提高用户对荷尔蒙避孕措施的坚持和满意度至关重要.
研究的目的:
- 审查当前和潜在的治疗干预措施,以管理使用荷尔蒙避孕药的个人非计划出血.
- 评估已知和新药在减少突破性出血事件中的有效性.
主要方法:
- 对研究的文献综述,研究了与荷尔蒙避孕药相关的非计划出血的治疗方法.
- 对非类固醇抗炎药物 (NSAIDs),荷尔蒙疗法以及多西环林,米费普里斯,特兰胺酸,他莫西芬,乌利普里斯塔酸盐和克洛米芬酸盐等替代药物的证据分析.
主要成果:
- 非类固醇抗炎药物 (NSAID) 和含有雌激素和孕激素的联合口服避孕药是标准的治疗方法.
- 初步证据表明,米费普里斯顿和特兰克萨姆酸可能对使用储存麦德洛西孕酸盐,植入物和子宫内器械的用户有效.
- 其他几种药物,包括多西环素,他莫西芬,乌利普里斯塔酸盐和克洛米芬酸盐,在小型研究中显示出潜力.
结论:
- 综合咨询对于管理用户期望和提高对荷尔蒙避孕药的满意度至关重要.
- 虽然NSAIDs和联合口服避孕药是常见的,但替代疗法需要进一步调查,以管理持续的非计划出血.
- 米菲普里斯和特兰克萨姆酸在特定的避孕方法方面表现特别有前途,尽管需要更多的研究.
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