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相关概念视频

Randomized Experiments01:13

Randomized Experiments

The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...

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随机试验比较鼻腔阻塞的下层轮整形技术:一个元分析.

Macario Camacho1, Yoseph A Kram2, Forrest D Craig3

  • 1Division of Otolaryngology, Tripler Army Medical Center, Honolulu, Hawaii, USA.

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概括

移除组织或外骨折的下部轮整形术显著改善鼻腔阻塞症状2-3年. 不去除组织的技术可能会导致症状复发,这表明需要进一步研究.

关键词:
这是一个元分析.鼻腔堵塞 鼻腔堵塞 鼻腔堵塞随机化试验是一种随机化试验.系统性审查 系统性审查轮塑料制造公司

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科学领域:

  • 耳鼻喉科 耳鼻喉科 耳鼻喉科
  • 鼻科 鼻科是指鼻科的专家.
  • 外科手术的结果

背景情况:

  • 鼻腔阻塞是影响生活质量的常见疾病.
  • 下部轮整形是一种用于缓解鼻腔阻塞的外科手术.
  • 不同的轮塑技术的长期主观结果需要系统的评估.

研究的目的:

  • 系统地审查长期 (1-3年) 对鼻阻塞下层轮整形术的主观结果的随机试验.
  • 对现有证据进行元分析.

主要方法:

  • 在PubMed/MEDLINE和其他五个数据库中进行系统的文献搜索.
  • 包括四个随机试验,包括2874名患者.
  • 在手术后2年和3年使用视觉模拟尺度 (VAS) 分析主观结果.

主要成果:

  • 涉及组织去除或外骨折 (microdebrider,粘膜下切除,外骨折) 的程序显示,在2年和3年后,VAS得分大约有80-83%的改善.
  • 无线电频率切除,这是一种不去除组织的技术,在2年内显示出最小的改善 (8.1%) 和在3年内略微增加VAS (12.2%),表明阻塞的潜在复发.
  • 微碎片,下切除和外裂技术始终使VAS得分从基线值约8.2-8.7降低至2年和3年约1.5-1.6分.

结论:

  • 清除组织或外骨折的低级轮整形技术可以在鼻腔阻塞症状中显著和持续的主观改善,长达3年.
  • 不去除组织或外骨折的技术可能与鼻腔阻塞的复发有关.
  • 需要进一步的研究,以充分阐明各种劣质轮塑造方法的长期疗效.