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Updated: Sep 20, 2025

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
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A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development

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优化诺特林剂量:基于药物遗传学,基于表型和标准剂量之间的比较.

Cornelis F Vos1,2,3, Marieke J H Coenen4, Sophie E Ter Hark5,6

  • 1Department of Psychiatry, Radboud University Medical Center, Reinier Postlaan 10, 6526 GC, Nijmegen, The Netherlands. niels.vos@radboudumc.nl.

Clinical pharmacokinetics
|May 25, 2025
PubMed
概括

使用药物遗传学或表型测量的个性化诺特林剂量比标准剂量更准确,用于在大型抑郁症中达到治疗性血度. 这两种方法都减少了变异性,并改善了治疗结果.

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