准备O/W/O乳液用于黄素 (Curcuma longa) 输送和体外消化能力测试
Kristýna Opustilová1, Barbora Lapčíková1, Daniela Sumczynski1
1Department of Food Technology, Faculty of Technology, Tomas Bata University in Zlin, Nam. T. G. Masaryka 5555, 760 01 Zlin, Czech Republic.
International journal of molecular sciences
|June 26, 2025
概括
与简单乳液相比,多重乳液提供更好的黄素输送,显示出更好的稳定性和消化能力. 这项研究突出了它们提高营养物质生物可用性的潜力.
科学领域:
- 食品科学与技术 食品科学与技术
- 合体和表面化学
- 营养科学 营养科学
背景情况:
- 黄素是一种强大的生物活性化合物,具有较差的生物利用性.
- 基于乳液的输送系统正在探索,以提高黄素的稳定性和吸收.
- 了解不同类型乳液的结构和消化特性对于优化输送至关重要.
研究的目的:
- 评估简单的油入水 (O/W) 和多重的油入水入油 (O/W/O) 乳液作为黄素输送的载体.
- 为了比较含有黄素的O/W和O/W/O乳液的稳定性,颗粒大小,质性和体外消化性.
- 评估从乳液中的黄素与新鲜和干燥的黄根粉末的体外消化能力.
主要方法:
- 使用差分扫描热量计 (DSC),动态光散射 (DLS) 和风湿学分析进行乳液表征.
- 在两种类型的乳液中确定可结水含量 (Wfs).
- 用高性能液态染色学 (HPLC) 监测的黄素在乳液和黄根粉的体外消化性研究.
主要成果:
- 与O/W/O乳液 (80.4%) 相比,O/W/O乳液的结水量显著降低 (23.7%).
- 多种O/W/O乳液表现出更高的稳定性和更大的平均表面直径 (约. 2x),而不是简单的O/W乳液.
- O/W/O乳液对于黄素的输送优越,在模拟的胃和肠道条件下达到50.6%的消化率,优于干燥的黄粉 (52.9-78.8% DMD),但不是新鲜的黄 (95.5% DMD).
结论:
- 与简单的O/W/O乳液相比,多种O/W/O乳液提供了更稳定,更有效的黄素输送矩阵.
- 多种乳液的复杂结构增强了黄素的稳定性,并改善了其体外消化能力.
- 这项研究支持多重乳液的潜力,作为提高黄素生物可用性的有希望的策略.
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