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Updated: Sep 17, 2025

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
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Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Published on: September 13, 2013

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在G蛋白合受体上探测抗体结合部位,使用遗传编码的可光激活的交叉链接器.

Victoria R Saca1,2, Jordan M Mattheisen1,2, Thomas Huber1

  • 1Laboratory of Chemical Biology and Signal Transduction, The Rockefeller University, New York, NY, USA.

Methods in molecular biology (Clifton, N.J.)
|July 2, 2025
PubMed
概括

研究人员开发了一种新的方法,用于绘制G蛋白结合受体 (GPCRs) 上的抗体结合部位的地图. 这种技术使用遗传密码扩展和可光激活的氨基酸来确定相互作用,帮助药物开发.

关键词:
珀鱼鱼鱼鱼鱼鱼鱼鱼鱼鱼鱼抗体是对抗体的一种.在Epitope的地图上.G蛋白结合受体的受体是G蛋白结合受体的受体.可光激活的交叉连接器

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