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Updated: Sep 15, 2025

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一个扩大的腹腔下区域支持在旋脑大脑中产后皮层内部神经元的迁移

JaeYeon Kim1,2, Aunoy Poddar1,3,4, Kadellyn Sandoval1,5

  • 1Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.

Nature neuroscience
|July 14, 2025
PubMed
概括

人类和灵长类动物的新生儿大脑具有独特的结构,即弧形,它支持内部神经元的长距离迁移. 这种弧形结构对于开发复杂大脑中发现的多样化的皮层内部神经元群体至关重要.

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Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
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