相关实验视频
Updated: May 2, 2026

10:10
Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
Published on: October 18, 2011
12.8K
在皮层中放射治疗期间早期时皮层的变化,来自MRI的平均扩散度和厚度
Chuangwei Dong1,2,3,4, Jin Liu2,5, Zong Cao2,5
1Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Journal of magnetic resonance imaging : JMRI
|July 21, 2025
概括
鼻癌的放射治疗导致早期叶结构变化,包括平均扩散率增加和皮质厚度降低. 这些变化随着时间的推移而恶化,并且在特定地区显示出早期的剂量依赖性关联.
科学领域:
- 神经成像是一种神经成像.
- 放射治疗瘤学 放射治疗瘤学
- 神经科学是一个神经科学.
背景情况:
- 鼻癌 (NPC) 的放射治疗 (RT) 经常导致叶 (TL) 损伤.
- 在RT期间TL的早期形态变化不太清楚.
- 识别这些变化可以帮助减轻长期的认知障碍.
研究的目的:
- 描述在RT期间TL的早期结构变化.
- 用皮质厚度 (CTh) 和皮质平均扩散率 (cMD) 来进行评估.
- 探索RT和TL结构变化之间的潜在剂量依赖关系.
主要方法:
- 对40名NPC患者进行了前性纵向研究.
- 3T MRI包括DTI和MPRAGE序列在治疗前,治疗中期和治疗后获得的.
- 在18个双边TL地区对CTh和cMD进行了基于表面的分析,并绘制了辐射剂量映射.
主要成果:
- 在整个治疗过程中观察到cMD的显著增加和CTh的减少,治疗后加剧.
- 早期显著的变化 (中期治疗) 在CTh的3/18区域和cMD的5/18区域被发现.
- 在纠正后,在右上神经 (cMD) 和左下神经 (CTh) 中发现了早期的剂量依赖性关联.
结论:
- 在TL的RT诱导的结构变化开始很早,并在整个治疗过程中进展.
- 统计学力量有限,但早期剂量关联需要进一步调查.
- 需要进行更大规模的研究,才能充分理解RT诱导的TL变化中的早期剂量反应动态.
相关概念视频
X-ray Imaging
7.7K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
7.7K
Magnetic Resonance Imaging
7.6K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
7.6K
Radiological Investigation II: MRI and Ventilation Perfusion Scan
1.0K
Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
1.0K
Imaging Studies I: CT and MRI
1.3K
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
1.3K
Imaging Studies for Cardiovascular System IV: CMRI
541
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
541
Imaging Studies IV: Magnetic Resonance Imaging
427
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
427

