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Updated: Sep 8, 2025

Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity
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调节性T细胞从自身反应性T细胞进行表观遗传重编程,缓解已建立的自身免疫力.

Tyler R Colson1, James J Cameron1, Hayley I Muendlein2

  • 1Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, United States of America.

JCI insight
|August 5, 2025
PubMed
概括

将效应性T细胞重新编程成调控性T细胞 (Tregs) 会产生稳定的ER-Tregs. 这些ER-Tregs通过利用它们保存的效应器功能和特异性,有效地治疗小鼠的自身免疫神经炎症.

关键词:
自身免疫性疾病是一种自身免疫性疾病.这是一种自身免疫力.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.免疫学 免疫学 免疫学炎症 炎症是一种炎症.在T细胞,T细胞.

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