孕期压力影响认知和行为
Curt A Sandman1, Elysia P Davis1,2
1333 City Drive West, Suite 1200, Department of Psychiatry & Human Behavior, University of California, Irvine, Orange, CA 92868, USA.
Future neurology
|August 7, 2025
概括
怀孕期间的早期生活压力可能会对胎儿发育产生负面影响,导致终身健康问题. 前性研究表明,产前压力会影响儿童的神经发育和认知功能.
科学领域:
- 疾病的发育起源 疾病的发育起源
- 神经科学是一个神经科学.
- 孕产妇和胎儿的医学
背景情况:
- 疾病发育起源 (DOD) 模型认为,早期生命暴露会影响终身健康.
- 大多数支持国防部的人类研究都是回顾性的,使用代用标记物,如出生体重.
- 新兴的前性研究调查子宫内疾病的直接影响.
研究的目的:
- 检查子宫内应激暴露的发育后果.
- 评估妊娠压力对神经发育的影响.
- 通过不利条件合成关于胎儿编程的证据.
主要方法:
- 综述最近关于妊娠压力的前性研究.
- 对测量怀孕中逆境心理社会和生物标志物的研究进行分析.
- 评估胎儿,婴儿和儿童的神经和认知结果.
主要成果:
- 胎儿暴露于心理和生物逆境显著影响神经发育.
- 孕期早期的压力与胎儿成熟延迟和婴儿认知能力受损有关.
- 产前压力与儿童大脑体积减少有关,影响学习和记忆领域.
结论:
- 胎儿暴露于压力深深影响着发育中的神经系统.
- 不良的子宫内疾病对神经发育和认知功能有持久的影响.
- 证据支持胎儿编程模型对与压力相关的健康结果进入童年及以后.
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