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Updated: Jul 1, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
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Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

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用单细胞Hi-C数据发现亚型的新型空间结构零意识不相似度测量.

Yongqi Liu, Victor Jin, Shili Lin

    bioRxiv : the preprint server for biology
    |August 8, 2025
    PubMed
    概括

    一个新的度量,结构零感知肯德尔的 (szKendall),通过区分真正的结构零和序列放弃来改进单细胞Hi-C数据的分析. 这增强了对基因组组织中细胞对细胞的变异性的理解.

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    相关概念视频

    Comparing Copy Number Variations and SNPs02:26

    Comparing Copy Number Variations and SNPs

    Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
    Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...