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Updated: Sep 9, 2025

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models
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产生编码抗HBV设计表观基因组的mRNA

Prashika Singh1, Tafadzwa Mlambo2, Kristie Bloom1

  • 1Wits/SAMRC Antiviral Gene Therapy Research Unit, Infectious Diseases and Oncology Research Institute (IDORI), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Methods in molecular biology (Clifton, N.J.)
|August 28, 2025
PubMed
概括

新的表观基因组编辑工具使用通过mRNA传递的设计表观基因组修饰剂 (DEM) 来准和静止慢性乙型肝炎病毒 (HBV) 复制. 这种方法为持续的HBV治疗提供了一个有前途的非变异性策略.

关键词:
CpG 岛屿其他国家没有HBV在体外转录

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