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Updated: Jan 17, 2026

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
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SPARC:可编程药物组合的多重负载ADC架构

Wenlong Sun1, Weining Weng2, Jing Shi3

  • 1HuaO Therapeutics, Shanghai 200441, China.

Bioconjugate chemistry
|September 17, 2025
PubMed
概括

协同有效载荷-抗体比度结合物 (SPARCs) 通过在最佳比率下提供多种药物,使得精确的组合癌症治疗成为可能. 与传统方法相比,这种方法提高了疗效,降低了毒性.

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