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癌症相关疲劳的认知行为疗法:治疗治疗意图的患者和晚期癌症患者之间的比较
Hannah B van der Pas1,2, Annemarie M J Braamse1,2, Gijs Bleijenberg3
1Department of Medical Psychology, Amsterdam UMC Location University of Amsterdam, Amsterdam, the Netherlands.
认知行为疗法 (CBT) 有效地减少与癌症相关的疲劳 (CRF). 然而,CBT对晚期癌症患者的疲劳严重程度和灾难性影响较小,与治疗治疗意图的人相比.
科学领域:
- 在瘤学瘤学.
- 心理学 心理学 心理学
- 行为医学是一种行为医学.
背景情况:
- 与癌症相关的疲劳 (CRF) 显著影响正在接受治愈治疗的患者和晚期癌症患者.
- 认知行为疗法 (CBT) 是一种公认的干预措施,用于缓解CRF在两个患者群体.
研究的目的:
- 为了比较治疗前的疲劳和认知行为因素,治疗治疗意图和晚期癌症患者之间的患者.
- 评估CBT在减少疲劳严重性的差异性有效性,在这两个组.
- 为了确定影响CBT反应的调解者,在患有不同癌症预后的患者中.
主要方法:
- 来自四个随机对照试验的CBT对CRF的数据汇总.
- 与治疗意图治疗的患者 (n=249) 和晚期癌症患者 (n=134) 之间的基线特征和疲劳水平的比较.
- 采用调节和调节调解分析来评估治疗效果和潜在机制.
主要成果:
- 在疲劳延续因素中观察到显著的基线差异,但不是疲劳严重程度,在两组之间.
- 晚期癌症患者在CBT后的疲劳严重程度下降较小,与治疗治疗意图的患者相比 (p=0.022).
- 在接受治疗的患者中,有治愈意图的CBT导致疲劳灾难的更大降低,而不是晚期癌症患者.
结论:
- 认知行为疗法在缓解晚期癌症患者的疲劳严重程度和灾难化方面表现出较低的有效性.
- 疲劳灾难化,一个关键的调解者,在晚期癌症患者中,CBT对CBT的影响较小.
- 需要进行进一步的研究,以提高晚期癌症患者中CRF的CBT疗效.
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