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相关概念视频

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

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Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
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Scanning Electron Microscopy01:07

Scanning Electron Microscopy

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A scanning electron microscope (SEM) is used to study the surface features of a sample by using an electron beam that scans the sample surface in a two-dimensional manner. Typically, areas between ~1 centimeter to 5 micrometers in width can be imaged. SEM can be used to image bacteria, viruses, tissues as well as larger samples like insects. Conventional SEM gives a magnification ranging from 20X to 30,000X and spatial resolution of 50 to 100 nanometers.
Fundamental Principles
Accelerated...
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相关实验视频

Updated: Jan 17, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
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使用电湿束扫描仪进行非机械光谱域光学连贯性断层扫描.

Samuel D Gilinsky, Eduardo J Miscles, Jan Bartos

    Optics express
    |September 23, 2025
    PubMed
    概括

    我们开发了一种新的电湿束方向镜,用于光谱域光学连贯断层扫描 (SD-OCT) 的横向扫描. 这种紧的非机械镜可以在不影响系统性能的情况下进行OCT成像.

    科学领域:

    • 光学和光子学 在光学和光子学.
    • 生物医学成像技术 生物医学成像技术
    • 微流体学 微流体学

    背景情况:

    • 光学连贯断层扫描 (OCT) 是一种强大的非侵入性成像技术.
    • 传统的OCT系统通常依赖于重的机械扫描机制.
    • 电湿光学为光学束转向提供了一个紧的,低功耗的,非机械的替代方案.

    研究的目的:

    • 为了展示电湿束转向镜的首次应用,用于横向扫描,在 OCT 系统的基板谱域中进行扫描.
    • 在一个OCT设置中评估电湿镜的性能.
    • 评估电湿光学对微型OCT应用的适用性,例如内镜OCT.

    主要方法:

    • 电湿束转向镜的集成到一个光谱域OCT系统中.
    • 使用1091nm,53nm带宽增益管理的非线性光纤放大器作为光源.
    • 用电湿镜对海上国家和地区系统的视野,轴分辨率和灵敏度进行表征.
    • 电湿镜实现了±6°的横扫描,应用电压为67V ±20V.

    主要成果:

    • 通过在台式SD-OCT系统中使用电湿镜成功实现横向扫描.
    • 电湿镜使得OCT能够在不降低关键系统性能指标的情况下获取图像.

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    Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
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    Author Spotlight: Characterizing Environmental Biofilm Mechanics Using Optical Coherence Elastography and its Applications in Wastewater Treatment
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  • 证明了在OCT使用电湿光学用于光束方向的可行性.

    • 结论:

    • 电湿束转向镜是一种可行且有效的技术,用于SD-OCT的横向扫描.
    • 这种非机械的方法非常适合开发紧而坚固的OCT系统.
    • 开发的系统显示了未来内镜和微型化OCT应用的前景.