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相关概念视频

Bacterial Flora of the Large Intestine01:29

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The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
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Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
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相关实验视频

Updated: Jan 16, 2026

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
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"没有"的食物是没有风险的吗? 无乳糖牛奶发酵调节肠道微生物群中的正常结肠在体外模型中

Flavia Casciano1, Lorenzo Nissen1,2, Alessandra Bordoni1,2

  • 1DiSTAL-Department of Agricultural and Food Sciences, Alma Mater Studiorum-University of Bologna, P.za G. Goidanich, 60, 47521 Cesena, Italy.

Microorganisms
|September 27, 2025
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概括

没有乳糖的牛奶消费可能会破坏健康个体的肠道微生物群,可能会增加失生症的风险. 这项研究建议避免无乳糖饮食,除非医疗需要,符合ESPEN的指导方针.

关键词:
这种细菌是Bifidobacterium spp.它们是Enterobacteriaceae的细菌.乳制品 乳制品是一种乳制品.我们的肠道微生物群.环球健康环球健康环球

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科学领域:

  • 微生物组研究的研究.
  • 食品科学 食品科学 食品科学
  • 人类健康 人类健康 人类健康

背景情况:

  • 越来越多的消费"免费"的食物的一般人口,由感知健康益处驱动.
  • 对无乳糖产品对健康消费者的风险和益处的了解有限.
  • 缺乏关于无乳糖牛奶对健康个体肠道微生物群的影响的研究.

研究的目的:

  • 研究无乳糖牛奶对健康人群肠道微生物群的潜在调节.
  • 分析肠道微生物种群和代谢物生产的变化.
  • 为了确定特定的微生物和分子驱动器的dysbiosis.

主要方法:

  • 在体外模拟消化和发酵.
  • 微生物学和代谢学方法的整合.
  • 微生物学指标和微生物化合物生产的分析.

主要成果:

  • 与含有乳糖的牛奶相比,无乳糖牛奶显著改变了结肠微生物群的组成.
  • 观察到有益细菌的减少,例如Bifidobacteriaceae和Lactobacillales.
  • 减少关键微生物代谢物的产生,包括酸和丁酸,这表明失生症风险增加.

结论:

  • 没有乳糖的牛奶消费可能会在健康个体中构成肠道失调的风险.
  • 这些发现支持目前的指导方针,建议那些没有被诊断为不耐受症的人不要进行常规的无乳糖饮食.
  • 该研究建立了一个新的体外模型,用于可持续和可翻译的微生物组研究.