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Updated: Jan 15, 2026

Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions
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Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions

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用核酸分离RX重复的相位分离.

Sumit Shil1, Mitsuki Tsuruta1, Ryosuke Suzuki1

  • 1Frontiers of Innovative Research in Science and Technology (FIRST) Konan University, 7-1-20 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.

Chemistry, an Asian journal
|October 9, 2025
PubMed
概括

蛋白质中的甘氨酸残留物是生物分子液体-液体相分离 (LLPS) 与G-四重复DNA的关键. 替代甘氨酸揭示了性质如何控制LLPS和液态固态相分离 (LSPS).

关键词:
基因结构 DNA结构 DNA结构液态-液态相隔离器 液态相隔离器液体-固体相分离方法 液体-固体相分离方法这是一种RX-repat.

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Author Spotlight: Characterizing DNA Replication of Pathogenic Repeats to Uncover Mechanisms of Replication Fork Stalling and Expansion05:22

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相关概念视频

Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
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