开发一种离散选择实验仪器,用于评估患者在精密瘤学的偏好.
Zahra Karimi Majd1, Nazila Yousefi1, Mohammad Peikanpour1
1Department of Pharmacoeconomics and Pharma Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iranian journal of pharmaceutical research : IJPR
|October 17, 2025
概括
患者对精密瘤学的偏好至关重要. 一个经过验证的工具确定了关键因素,如治疗机会,成本,预期寿命增长和个性化医学的生活质量改善.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 以患者为中心的护理
背景情况:
- 患者的偏好对于评估精准医学 (PM) 干预措施以及临床和技术因素至关重要.
- 了解患者的优先事项是成功实施个性化瘤学的关键.
研究的目的:
- 在精密瘤学中识别和优先考虑患者重要的属性.
- 开发和验证一个标准化的声明偏好仪器,用于评估患者在精密瘤学的偏好.
主要方法:
- 系统的文献审查,以提取精密瘤学的关键属性.
- 使用35名专家的德尔菲方法,使用利克特比例问卷来确定属性优先级.
- 基于优先级属性的离散选择实验 (DCE) 仪器的开发和验证.
主要成果:
- 开发了一个基于共识的DCE工具,包括四个属性和14个级别.
- 确定了关键属性:治疗的可访问性,自费支出,预期寿命的变化和生活质量的变化.
- 该仪器为评估患者在精密瘤学方面的偏好提供了一个强大的衡量标准.
结论:
- 开发的DCE问卷反映了伊朗专家在精密瘤学方面的主要偏好.
- 这种经过验证的仪器可以用于评估患者的偏好和支付意愿 (WTP) 在精密瘤学环境中.
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