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缺血性肠道组织的超谱和基于机器学习的分类.
Valery V Shupletsov1, Ilya A Goryunov1, Nikita A Adamenkov1,2
1Orel State University, Research & Development Center of Biomedical Photonics, Orel, Russia.
Journal of biomedical optics
|November 3, 2025
概括
超光谱成像 (HSI) 与机器学习 (ML) 结合,客观地评估在手术期间的肠道活力. 这种非侵入性工具可以改善手术决策,并减少肠道缺血病例中不必要的组织切除.
科学领域:
- 医学成像医学成像
- 进行外科评估.
- 生物医学工程 生物医学工程
背景情况:
- 肠道组织活力的内科手术评估对于确定肠道缺血的切除程度至关重要.
- 目前的主观方法缺乏准确性,无法为可靠的外科决定做出决定.
研究的目的:
- 开发和验证与机器学习 (ML) 集成的高光谱成像 (HSI) 系统.
- 客观地评估肠壁活力,并区分可逆性和不可逆性缺血.
主要方法:
- 一个便携式的HSI系统从诱导肠道缺血症的老鼠模型中获取了光谱数据.
- 用两波长算法计算组织氧和度.
- ML管道 (PCA和XGBoost) 分类光谱数据训练在组织学验证上.
主要成果:
- 长期缺血时,组织和率显著下降 (12小时时66%至21%).
- 对于不同的缺血状态,ML分类实现了高准确度 (95-98%).
- HSI-ML图与组织和和组织学相关;初步的人体测试显示敏感性.
结论:
- 与ML相结合的HSI提供了一个有效的,非侵入性的工具,用于实时的手术内肠道活力评估.
- 这种方法提高了手术决策的客观性,并可以最大限度地减少不必要的切除.
相关概念视频
Classification of Connective Tissues
The connective tissues have different properties and functions in the human body. They are broadly categorized into proper, supporting, or fluid connective tissues.
Connective Tissue Proper
Connective tissue proper is the most abundant class of connective tissues. As its name implies, it predominantly connects different tissues in the body. Depending on the cell types, ground substance, viscosity, and fiber types in the ECM, connective tissue proper is further categorized into loose and dense.
Connective Tissue Proper
Connective tissue proper is the most abundant class of connective tissues. As its name implies, it predominantly connects different tissues in the body. Depending on the cell types, ground substance, viscosity, and fiber types in the ECM, connective tissue proper is further categorized into loose and dense.
Classification of Leukocytes
Leukocytes are classified into two groups based on the presence or absence of cytoplasmic granules. Granular leukocytes, which contain granules, belong to the myeloid lineage and are divided into three subtypes: neutrophils, eosinophils, and basophils. These cells are roughly spherical and characterized by the granules in their cytoplasm.
Neutrophils are the most abundant type of granular leukocytes, comprising 50-70% of all leukocytes. They feature small, evenly distributed granules and a...
Neutrophils are the most abundant type of granular leukocytes, comprising 50-70% of all leukocytes. They feature small, evenly distributed granules and a...
Classification of Systems-I
Linearity is a system property characterized by a direct input-output relationship, combining homogeneity and additivity.
Homogeneity dictates that if an input x(t) is multiplied by a constant c, the output y(t) is multiplied by the same constant. Mathematically, this is expressed as:
Homogeneity dictates that if an input x(t) is multiplied by a constant c, the output y(t) is multiplied by the same constant. Mathematically, this is expressed as:

