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相关概念视频

Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

4.8K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
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Lipid-derived Compounds in the Human Body01:31

Lipid-derived Compounds in the Human Body

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Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
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What are Lipids?01:38

What are Lipids?

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Overview
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相关实验视频

Updated: Jan 12, 2026

Lipidomics and Transcriptomics in Neurological Diseases
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Lipidomics and Transcriptomics in Neurological Diseases

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在生物标志物发现中探索脂管学.

M Malarvannan1, Bhanu Teja Naik Sabavath1, Navratan Soni1

  • 1Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER)-Kolkata, West Bengal 700054, India.

Clinica chimica acta; international journal of clinical chemistry
|November 6, 2025
PubMed
概括

脂质学为健康和疾病中的脂质变化提供了洞察力,有助于发现糖尿病和癌症等疾病的生物标志物. 在临床整合方面仍然存在挑战,但脂管学对早期诊断和向治疗有希望.

关键词:
发现生物标志物的发现.生物标志物验证的验证利皮多米克 (Lipidomics) 是一种消化剂.代谢障碍 代谢障碍 代谢障碍

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Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
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Shotgun Lipidomics of Rodent Tissues
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Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
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科学领域:

  • 系统生物学 系统生物学
  • 生物化学 生物化学
  • 临床诊断 临床诊断 临床诊断

背景情况:

  • 脂质是调节炎症,新陈代谢和信号的生物活性分子.
  • 脂质学研究了脂质物种及其在健康和疾病中的动态变化.
  • 脂管组学是一个强大的工具,用于在临床环境中识别新生物标志物.

研究的目的:

  • 在各种疾病中识别疾病特异性脂质特征和生物标志物.
  • 在临床应用中检查脂质组学的意义.
  • 讨论临床实践中脂管学的挑战和翻译潜力.

主要方法:

  • 研究的脂质组标记物的深入摘要.
  • 脂管学方法论的比较分析.
  • 讨论脂质组生物标志物验证过程.

主要成果:

  • 脂管学已经确定了代谢,心血管,神经退行性,癌症和炎症性疾病的潜在生物标志物.
  • 在了解脂质在疾病中的作用方面取得了重大进展.
  • 确定了阻碍常规临床整合的挑战.

结论:

  • 脂管学驱动的生物标志物发现桥梁脂质研究和临床应用.
  • 脂组学在风险评估,早期诊断和向治疗方面表现有前途.
  • 对于例行临床翻译,需要进一步的研究和验证.