创建健康调节后生物的综合工程方法
Michael Leonidas Chikindas1,2, Diana E Roopchand3, Santosh Kumar Tiwari4
1Health Promoting Naturals Laboratory, School of Environmental and Biological Sciences, Rutgers State University, New Brunswick, New Jersey, USA.
Molecular nutrition & food research
|November 18, 2025
概括
后生物质,无活化的微生物成分,提供与益生菌相比的健康益处,提高了安全性和稳定性. 研究探讨了它们的机制,生物活性化合物和各种应用的失活方法.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 生物技术是生物技术.
背景情况:
- 后生物质因安全性,稳定性和保质期优势而成为活益生菌的替代品.
- 它们通过利用微生物中的生物活性成分来提供类似的健康益处.
研究的目的:
- 提供对后生物研究的全面审查,包括定义,机制和应用.
- 讨论微生物失活的方法,并比较后生菌与益生菌.
主要方法:
- 综述关于后生物制剂,它们的作用机制和生物活性成分的当前文献.
- 对各种微生物失活技术 (热,非热,混合) 的分析.
- 对后生菌与益生菌的健康益处和安全概况的比较评估.
主要成果:
- 后生物质通过SCFA,EPS和特定蛋白质等成分调节宿主生理,影响肠道屏障,免疫力,新陈代谢和炎症.
- 各种无活化方法可以保持后生物生物活性,同时确保微生物的安全性.
- 无活化后生物制剂表现出与活益生菌相比具有可比或优越的健康益处和安全性.
结论:
- 后生物质是健康和生物技术应用的一个有前途的途径,比活益生菌有优势.
- 定义和生产流程的标准化对于未来的发展至关重要.
- 需要进一步的研究,才能充分发挥后生菌在临床和营养环境中的潜力.
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