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相关概念视频

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

14.0K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

235
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
235
Blood Transfusion01:15

Blood Transfusion

2.1K
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
2.1K
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

247
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
247
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

196
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
196

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相关实验视频

Updated: Jan 10, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

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儿科大规模输血协议:叙述审查和拟议的算法

Michaela Forgione1, Nicholas J Larson1, Amelia Collings2

  • 1Department of Surgery, Regions Hospital, Saint Paul, MN, USA.

The American surgeon
|November 20, 2025
PubMed
概括
此摘要是机器生成的。

出血是导致死亡的主要原因,特别是在儿童中. 本综述检查了儿科大规模输血协议 (pMTP),并提出了一个 pMTP 激活的算法,因为研究有限.

关键词:
血液 血液 血液 血液 血液发生出血 发生出血创伤急性护理的急性护理

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A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
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A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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Last Updated: Jan 10, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

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A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
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A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

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A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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科学领域:

  • 创伤外科 手术 创伤外科
  • 儿科重症监护中心儿童重症监护中心
  • 血液性冲击管理 血液性冲击管理

背景情况:

  • 出血是美国可预防死亡的主要原因.
  • 儿科患者患有不成比例的高出血死亡率.
  • 关于儿科创伤复苏和大规模输血协议 (MTP) 的文献不如成人开发.

研究的目的:

  • 审查有关儿科大规模输血协议 (pMTP) 的当前文献.
  • 确定关于pMTP的研究现状.
  • 为儿童创伤中pMTP激活提供一个框架.

主要方法:

  • 关于儿科MTP的系统性文献综述.
  • 创伤和儿科手术的内容专家开发了一种临床算法.
  • 评估现有证据并确定研究缺口.

主要成果:

  • 目前关于pMTP的文献有限.
  • 提出了一个专家开发的pMTP激活算法.
  • 确定了对儿科患者pMTP激活的验证评分系统的需求.

结论:

  • 需要进一步研究以建立基于证据的pMTP指南.
  • 拟议的算法作为pMTP激活的临时解决方案.
  • 标准化和验证的协议对于改善儿科创伤复苏的结果至关重要.