C-Termini

Shravan R Dommaraju1,2,3, Sanath K Kandy4, Hengqian Ren3,5

  • 1Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

ACS central science
|December 4, 2025
PubMed
概括

研究人员阐明了达酸生物合成,一种独特的基修饰. 他们发现了能够为和蛋白质设计新的C-终端的酶,扩大了合成生物学应用.

相关概念视频

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Pre-mRNA Processing: Modification of pre-mRNA Ends

In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
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Eukaryotic cells can degrade proteins through several pathways. One of the most important amongst these is the ubiquitin-proteasome pathway. It helps the cell eliminate the misfolded, damaged, or unwarranted cytoplasmic proteins in a highly specific manner.
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