生殖尿路病理学全幻灯片成像: 一个基于云的数字化工作流程,用于资源有限的设置.
Aisha Memon1, Talat Zehra2, Sarosh Moeen1
1Department of Pathology and Laboratory Medicine, The Aga Khan University Hospital, Karachi, Pakistan.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|December 6, 2025
概括
将生殖尿液玻璃幻灯片数字化成全幻灯片图像 (WSI) 能够进行研究和教育. 这种方法通过可访问的数字格式,促进了更好的诊断共识,特别是在资源有限的环境中.
科学领域:
- 病理学 病理学 病理学
- 数字健康数字健康
- 医疗成像医学成像
背景情况:
- 生殖尿路病理传统上依赖于物理玻璃幻灯片.
- 数字化为加强研究,教育和知识共享提供了潜力.
- 远程病理学和数字图像解释是新兴领域.
研究的目的:
- 为研究,教育和知识共享而数字化生殖尿液玻璃幻灯片.
- 为了评估从数字化幻灯片中生成的全幻灯片图像 (WSI) 的实用性.
- 评估在资源有限的环境中使用数字病理学的可行性.
主要方法:
- 一项观察性研究使用31个脏活检核和21个前列腺组织核进行.
- 染色幻灯片的视频被录制并上传到一个开源平台,以创建WSIs.
- 三位病理学家独立审查了WSIs,使用卡帕统计数据评估观察者间的协议.
主要成果:
- 病理学家A与脏污点的参考诊断达成100%的一致性.
- 病理学家B显示H&E的一致性为77%,其他污点的一致性为74%.
- 病理学家C报告说,对于脏和前列腺活检,不同染料的高一致性 (74-100%).
结论:
- 全幻灯片图像 (WSIs) 可以通过可共享链接查看,包括在智能手机上.
- 数字化有助于在诊断方面达成共识,使资源有限的地区受益.
- 数字病理学平台可以增强生殖尿路病理学的协作和诊断准确性.
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