针对泛性焦虑障碍的数字认知行为治疗:一项随机临床试验
E Marie Parsons1, Tali Ball2, Jenna Carl2
1Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts.
JAMA network open
|December 15, 2025
概括
通过智能手机提供的数字认知行为疗法 (DCBT) 显著降低了一般性焦虑障碍 (GAD) 的成年人焦虑症状. 这种可访问的DCBT计划为GAD治疗提供了有前途的公共卫生效益.
科学领域:
- 心理健康 心理健康
- 数字治疗学数字治疗学
- 临床心理学 临床心理学
背景情况:
- 通用焦虑症 (GAD) 是一种慢性精神健康状况,对像认知行为疗法 (CBT) 这样的一线治疗方法的获取有限.
- 数字CBT (DCBT) 计划提供了一种潜在的解决方案,以克服治疗障碍并扩大有效疗法的覆盖范围.
研究的目的:
- 为了评估智能手机提供的DCBT程序的有效性,与治疗GAD的积极精神教育控制相比.
- 评估接受DCBT的参与者的症状严重程度和缓解率.
主要方法:
- 一个单盲,分散的随机临床试验,涉及351名被诊断患有GAD的成年人.
- 参与者被随机分配1:1接受通过智能手机自主定制的DCBT或在线心理教育干预.
- 结果在10周和24周使用GAD-7焦虑严重程度尺度和CGI-I缓解状态尺度来衡量结果.
主要成果:
- 在10周 (科恩d=1.09) 和24周 (科恩d=0.96) 两周,DCBT显著降低了GAD-7焦虑评分.
- 在DCBT组中,缓解率明显高:在10周后为71.0%,在24周后为77.7%,而对照组分别为34.6%和52.0%.
- 这些好处具有统计学意义 (P < .001),并在研究期间持续存在.
结论:
- 智能手机提供的DCBT是对GAD的有效治疗方法,在焦虑症状中提供了显著而持久的改善.
- 该DCBT计划显示出对公共健康的巨大潜力,解决了对基于证据的CBT的访问限制.
- 这种数字干预代表了一种可扩展和可访问的选择,对于患有一般性焦虑障碍的人来说.
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