Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Steady, Laminar Flow Between Parallel Plates01:17

Steady, Laminar Flow Between Parallel Plates

755
Understanding steady, laminar flow between parallel plates is essential for analyzing and designing flow in narrow rectangular channels, commonly found in various water conveyance and drainage systems. The Navier-Stokes equations govern fluid motion and are generally challenging to solve due to their nonlinearity. However, simplifications are possible in certain cases, like the steady laminar flow between parallel plates. For this scenario, we assume steady, incompressible, laminar flow.
755

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A microphysiologic human cervical model recapitulates microbial, immune, and pathogenic properties of sexually transmitted infections.

Science advances·2026
Same author

BEADS: An Interactive Semi-Automated Workflow for 3D Fibrin Angiogenesis Assays Enabling Co-Culture and Directionality Analysis.

bioRxiv : the preprint server for biology·2025
Same author

Anatomical 3D Reconstruction of Murine Lymph Nodes for Visualization, Quantitation, and Numerical Simulation.

bioRxiv : the preprint server for biology·2025
Same author

Confocal-Compatible Workflow for Sectioning, Staining, and Imaging Serial Vibratome Sections for 3D Anatomical Reconstruction of the Lymph Node.

bioRxiv : the preprint server for biology·2025
Same author

Protein Language Models are Accidental Taxonomists.

bioRxiv : the preprint server for biology·2025
Same author

Democratizing Organ-On-Chip Technologies With a Modular, Reusable, and Perfusion-Ready Microphysiological System.

Advanced healthcare materials·2025

相关实验视频

Updated: Jan 8, 2026

Parallel-plate Flow Chamber and Continuous Flow Circuit to Evaluate Endothelial Progenitor Cells under Laminar Flow Shear Stress
12:43

Parallel-plate Flow Chamber and Continuous Flow Circuit to Evaluate Endothelial Progenitor Cells under Laminar Flow Shear Stress

Published on: January 17, 2012

44.2K

模块化并行板流室具有可调的基板机械和定义的剪切应力.

Bryan J Ferrick1, Jason P Gleghorn1

  • 1Department of Biomedical Engineering, University of Delaware, Newark, DE 19713.

bioRxiv : the preprint server for biology
|December 18, 2025
PubMed
概括

这项研究引入了一个新的模型来测试细胞如何应对同时发生的机械力. 该装置允许独立控制细胞外矩阵刚度和流体剪切应力,揭示细胞行为上的协同效应.

科学领域:

  • 生物材料科学 生物材料科学
  • 细胞生物学 细胞生物学
  • 生物物理学的生物物理.

背景情况:

  • *当前的实验室模型经常独立研究细胞外矩阵 (ECM) 刚性和流体剪切应力 (FSS).
  • * 这限制了对应多个线索的细胞机械传导的理解.
  • *存在对能够独立控制和应用多个机械刺激的模型的需求.

研究的目的:

  • * 开发和验证一种具有可调节聚烯胺 (PAA) 基底的新型平行板流室.
  • * 为了使基质刚度和FSS的独立控制,用于研究细胞反应.
  • * 为了研究同时发生的机械信号对细胞行为的协同效应.

主要方法:

  • * 制造了一个平行板流室与PAA基板.
  • * 描述了PAA的机械特性,并证实了对Madin-Darby犬细胞生长的支持.
  • *使用粒子图像速度计验证了受控的FSS应用.
  • *分析F-actin组织以量化细胞反应.

主要成果:

  • *PAA基板在各种硬度上表现出可控制的机械性能.
  • * 流室设计保持了可预测的流体通道高度,以实现精确的FSS应用.
关键词:
2D微流体流体室 2D微流体流体室在ECM上,硬度是ECM的硬度.流体剪切应力 流体剪切应力在机械传导的体外模型中.

更多相关视频

In Vitro Model Integrating Substrate Stiffness and Flow to Study Endothelial Cell Responses
08:53

In Vitro Model Integrating Substrate Stiffness and Flow to Study Endothelial Cell Responses

Published on: July 19, 2024

800
Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions
11:51

Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions

Published on: February 22, 2018

9.1K

相关实验视频

Last Updated: Jan 8, 2026

Parallel-plate Flow Chamber and Continuous Flow Circuit to Evaluate Endothelial Progenitor Cells under Laminar Flow Shear Stress
12:43

Parallel-plate Flow Chamber and Continuous Flow Circuit to Evaluate Endothelial Progenitor Cells under Laminar Flow Shear Stress

Published on: January 17, 2012

44.2K
In Vitro Model Integrating Substrate Stiffness and Flow to Study Endothelial Cell Responses
08:53

In Vitro Model Integrating Substrate Stiffness and Flow to Study Endothelial Cell Responses

Published on: July 19, 2024

800
Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions
11:51

Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions

Published on: February 22, 2018

9.1K
  • *基板刚度和FSS协同增加了F-actin丝长.
  • * 刚度和FSS对F-actin丝宽度表现出独立的影响.

    • 结论:

    • * 开发的模型有效地允许独立和可调节的控制基板刚度和FSS.
    • * 该系统为研究并发机械力对细胞行为的影响提供了有价值的工具.
    • * 发现突出了ECM刚性和FSS在调节细胞细胞骨组织中的协同关系.