重新思考大脑区域在理解功能组织中的中心作用
Benjamin Yost Hayden1,2, Sarah R Heilbronner1,2, Seng Bum Michael Yoo3,4,5,6
1Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.
Nature neuroscience
|December 23, 2025
概括
大脑区域不是大脑功能的唯一组织者. 认知神经科学应该考虑其他原则,如梯度和网络,以更全面地了解大脑.
科学领域:
- 认知神经科学 认知神经科学
- 系统神经科学 系统神经科学
- 神经解剖学是一个神经解剖学.
- 电力生理学 电力生理学
背景情况:
- 独特的大脑区域的概念对于理解大脑功能至关重要.
- 目前的模型通常依赖于细胞架构和连接来进行大脑分片.
研究的目的:
- 挑战大脑区域在认知和系统神经科学中的中心作用.
- 探索大脑功能的其他组织原理.
- 重新评估大脑区域分片和认知功能之间的联系.
主要方法:
- 神经解剖学的分析
- 电生理学记录 电生理学记录
- 对关于大脑分片和认知功能的现有文献进行批判性审查.
主要成果:
- 神经解剖学和电生理学很少产生一致的大脑区域定义.
- 大脑区域只是几个组织原则中的一个,以及梯度,网络,层,列和补丁.
- 将大脑区域分片与认知功能联系在一起的证据不如人们普遍认为的那么强大.
- 认知功能通常是在分布式网络中实现的,或者遵循与离散大脑区域无关的组织原则.
结论:
- 传统上对大脑区域 (实现) 的关注可能不足以全面了解大脑.
- 像宏观梯度和分布式网络这样的替代组织原则至关重要.
- 未来的认知和系统神经科学研究应该采用一个超越现实化的更广泛的框架.
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