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Updated: Jan 7, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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药物开发 药物开发

Elizabeth E Evans1, Terrence L Fisher1, Vikas Mishra1

  • 1Vaccinex, Inc., Rochester, NY, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
PubMed
概括

塞马福林4D (SEMA4D) 阻断抗体pepinemab在治疗神经退行性疾病,如阿尔茨海默氏症,通过减少神经炎症和改善认知功能,显示出有前景. 临床试验表明,在早期阿尔茨海默病患者中,显著的认知效益和生物标志物改善.

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