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Updated: Jan 7, 2026

Porous Silicon Microparticles for Delivery of siRNA Therapeutics
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Porous Silicon Microparticles for Delivery of siRNA Therapeutics

Published on: January 15, 2015

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微调脂质涂层多孔纳米粒子用于siRNA输送.

Pouya Dehghankelishadi1, Parisa Badiee1, Shiying Qiao1

  • 1Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.

Advanced healthcare materials
|December 26, 2025
PubMed
概括

这项研究改进了多孔纳米粒子 (pSiNPs) 用于癌症siRNA输送. 新的脂质配方在小鼠中改善了瘤积累,提供了一个有希望的,耐受良好的癌症治疗策略.

关键词:
乳腺癌 乳腺癌 乳腺癌脂质涂层是一种脂质涂层.有孔的纳米粒子.小小的干扰RNA可以干扰RNA.

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相关概念视频

siRNA - Small Interfering RNAs02:30

siRNA - Small Interfering RNAs

Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the...
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