Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Farmers' Perspectives on Chronic Pain and Chronic Pain Management Strategies.

Journal of agromedicine·2026
Same author

Cumulative impacts of early-life interpersonal adversity and persistent/recurrent pain in children: a longitudinal normative modelling study from the ABCD study cohort.

Pain·2026
Same author

Brain atrophy and clinical diagnosis independently predict default mode network failure across the Alzheimer's disease continuum.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

Evaluating Artificial Intelligence for Sepsis Prediction in Emergency Departments: A Systematic Review and Meta Analysis.

Journal of medical systems·2026
Same author

Beyond Symptom Reduction: A Qualitative Study of Refugees' Experiences of a Trauma-Informed Community-Based Pain Management Program.

European journal of pain (London, England)·2026
Same author

Efficacy and Safety of Bisphosphonates for Complex Regional Pain Syndrome : A Systematic Review and Meta-analysis.

Annals of internal medicine·2025

相关实验视频

Updated: Jun 14, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

29.1K

复杂区域性疼痛综合征中的白物质结构:一个高角度分辨率和基于固定的研究.

Audrey P Wang1,2, Michael Green2,3, Peter Humburg2,4

  • 1Biomedical Informatics and Digital Health, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Westmead, New South Wales, Australia.

European journal of pain (London, England)
|December 29, 2025
PubMed
概括

复杂区域性疼痛综合征 (CRPS) 中的大脑结构与健康个体相比没有显著差异. 这些发现表明,白质变化不太可能在CRPS中具有临床意义,而是指向功能性改变.

关键词:
在CRPS中,我们可以使用CRPS.扩散扩散是一种扩散.固定器 固定器 固定器使用阿片类药物使用.白质是白色物质的组成部分.

更多相关视频

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
07:12

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Published on: January 21, 2020

8.3K
Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
08:33

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

1.6K

相关实验视频

Last Updated: Jun 14, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

29.1K
Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
07:12

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Published on: January 21, 2020

8.3K
Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
08:33

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

1.6K

科学领域:

  • 神经科学是一个神经科学.
  • 医疗成像医学成像
  • 疼痛研究 疼痛研究

背景情况:

  • 复杂区域性疼痛综合征 (CRPS) 通常被概念化为感官系统障碍.
  • 以前的研究表明,CRPS患者的大脑结构和功能存在差异,但研究结果不一致.

研究的目的:

  • 为了研究CRPS患者和健康对照者之间大脑中的白质结构差异.
  • 为了确定白质结构变化是否与CRPS症状或阿片类药物使用有关.

主要方法:

  • 分析高角分辨率扩散成像 (HARDI) 数据的横截面研究.
  • 采用基于fixel的分析方法来分析大脑白质结构.
  • 包括42名参与者 (CRPS患者和健康对照).

主要成果:

  • 在CRPS患者和对照人群之间没有发现扩散度的显著差异.
  • 纤维密度横截面测量在各组之间是统计学上同等的.
  • CRPS 症状和阿片类药物使用并没有通过检测到的白质结构差异来解释.

结论:

  • 这项研究的大型样本和先进的方法增加了对研究结果的信心.
  • 结果挑战了永久性大脑结构变化的概念,阻碍了CRPS恢复.
  • 功能性神经变化,而不是白质结构变化,可能是CRPS缺陷的关键,建议基于运动的疗法.