早期青春期发育是男孩和女孩精神病类似经历的危险因素
Eric R Larson1,2, Natasha Chaku1,2, Alexandra Moussa-Tooks1,2,3
1Department of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, Indiana.
Biological psychiatry global open science
|January 16, 2026
概括
早期青春期在两性中都增加了类似精神病的经历 (PLE),而男性更快的青春期节奏也会增加PLE的风险. 了解这些青春期成熟因素是早期识别和预防风险青少年战略的关键.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 精神病学是一个精神病学.
背景情况:
- 青春期是精神病的已知风险因素,但之前的研究缺乏详细的机制.
- 对于具体的青春期时间和节奏如何影响风险的理解有限.
研究的目的:
- 调查青少年青春期时间和节奏与精神病类经历 (PLEs) 之间的关联.
- 检查这些跨生物性别的关联.
主要方法:
- 在青少年大脑认知发展 (ABCD) 研究中利用了11,758名年轻人的数据.
- 采用性别特定的线性混合效应和负双项多层模型来分析青春期发育和PLE.
主要成果:
- 较早的青春期时间与两性中PLE增加相关.
- 晚期青春期的时间与两性中PLE的减少相关.
- 较快的青春期节奏与男孩较少的PLEs有关;较早的上腺动与女孩更多的PLEs有关.
结论:
- 早期的青春期时间和男性更快的青春期节奏与增加的PLE有关.
- 了解上腺在青春期成熟中的作用对于识别和预防青少年精神病风险至关重要.
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