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Updated: Jan 20, 2026

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使用连续排序概率得分验证基于生理学上的药理动力学模型:超出正确的平均值

Laurens Sluijterman1, Marjolein van Borselen2, Rick Greupink2

  • 1IQ Health, Section Biostatistics, Radboud University Medical Center, Nijmegen, the Netherlands.

CPT: pharmacometrics & systems pharmacology
|January 19, 2026
PubMed
概括

这项研究引入了一种新的验证方法,用于使用连续排列概率得分 (CRPS) 的生理基础药理动力学 (PBPK) 模型. 这种方法对药物开发更严格地量化模型性能.

关键词:
连续排名的概率得分连续排名的概率得分.评估框架 评估框架基于生理学的药物动力学模型.验证验证的时间

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