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  • 1Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle-Upon-Tyne NE1 7RU, UK.

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科学领域:

  • 医学成像分析分析 医学成像分析
  • 量化特征提取量化特征提取
  • 瘤学研究的研究.

背景情况:

  • 放射学提供了一种新的方法来识别喉癌的成像生物标志物.
  • 目前的研究系统地审查了喉状细胞癌中的放射学应用.

研究的目的:

  • 系统地审查喉癌中的放射学文献.
  • 评估放射学在瘤分期,预后,复发预测和治疗反应中的应用.

主要方法:

  • 在MEDLINE和EMBASE数据库中进行搜索 (2025年5月).
  • 包括使用CT,PET/CT或MRI进行放射性特征提取的研究 (2010年1月至2024年1月).
  • 不包括病例报告,综述,临床前研究以及缺乏明确方法的研究.

主要成果:

  • 20项研究符合纳入标准;大多数使用基于CT的放射学,其中7项包括PET/CT.
  • 放射性模型在T分期,生存预测和局部失效方面显示了中高的准确性.
  • 关键特征包括,斜率和纹理指标;限制是可变性,有限的验证和小样本.

结论:

  • 放射学是喉癌的一个有前途的非侵入性生物标志物.
  • 方法的异质性需要改善标准化和多中心验证以临床实施.