使用所有检查计算的较高的状伤检测率与结肠镜后结肠直肠癌的风险较低有关:来自新罕布什尔州结肠镜注册表的数据
Rachael Hagen1, Douglas K Rex2, Todd A MacKenzie3
1Department of Medicine, University of Connecticut, Farmington, CT, USA.
Clinical and translational gastroenterology
|January 30, 2026
概括
在所有结肠镜检查中,较高的状状病变检测率 (SSLDR-A) 与结肠镜后结肠直肠癌 (PCCRC) 的风险降低有关. 内镜医生应该以6%的SSLDR-A为目标,有8.0%或更高的愿望.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 使用所有结肠镜检查 (SSLDR-A) 来检测形形病变的检测率可能是一个更简单的质量指标,而不是仅使用查检查 (SSLDR-S).
- 这一指标有可能预测结肠镜后结肠直肠癌 (PCCRC) 风险.
研究的目的:
- 调查内镜专用SSLDR-A与PCCRC的风险之间的关联.
- 验证SSLDR-A作为预测PCCRC风险的质量指标.
主要方法:
- 分析了来自新罕布什尔州结肠镜注册处 (NHCR) 的115,585名患者,进行了索引结肠镜检查.
- 计算了内镜师特定的SSLDR-A和SSLDR-S,并分为五分之一.
- 考克斯回归模型用于评估PCCRC的危险性,并根据患者年龄和性别等共变量进行调整.
主要成果:
- 更高的SSLDR-A和SSLDR-S率与较低的PCCRC风险有关.
- 在对共变量进行调整后,较高的SSLDR-A与与参考组相比显著较低的PCCRC危险比率有关 (SSLDR-A <1.5%).
- 最高的SSLDR-A和SSLDR-S五分位数 (8.0%+) 显示对PCCRC有类似的保护.
结论:
- 由内镜师进行的高SSLDR-A的结肠镜检查与PCCRC的风险降低有关.
- SSLDR-A已被验证为用于预测PCCRC风险的质量指标.
- 建议SSLDR-A为6%,其中8.0%或更高被认为是理想的.
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