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Updated: Feb 28, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
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m5C-修饰的tRF3b-CysGCA-23 通过通过稳定RBM4抑制H3K18乳糖分来抑制膀癌恶性病变

Xiaoling Ying1,2, Yapeng Huang3, Jian Huang4,5

  • 1Department of Urology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 27, 2026
PubMed
概括

一种新型分子,m5C修饰的tsRNA (mtRC),在膀癌 (BC) 中被降低调节,并起到瘤抑制作用. 它通过mtRC/RBM4/H3K18la/IL1RAP&VASH2轴发挥作用,为BC提供了潜在的治疗点.

关键词:
希斯的乳酸化 希斯的乳酸化在NSUN6中在RBM4中使用RBM4.膀癌:膀癌是一种癌症.m5C‐tRF3b‐CysGCA‐23 (mtRC) 的使用情况

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