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Updated: Mar 7, 2026

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在神经发育过程中,WWP1功能增益通过TGFβ途径驱动发育性基

Ki Hurn So1, Seungbok Lee2,3, Jiayi Wong1

  • 1Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, 37673, Republic of Korea.

Cell death discovery
|March 5, 2026
PubMed
概括

过度活跃的WWP1通过损害神经元迁移和生存,导致神经发育问题. 降低TGFβ通路的调节是关键,WWP1变异与发育和性脑病症有关.

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