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Updated: Mar 10, 2026

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scDIAGRAM:检测来自单个单细胞Hi-C矩阵的染色体组件,没有归算或参考特征

Yongli Peng1, Yujing Deng2, Menghan Liu2

  • 1Beijing International Center for Mathematical Research (BICMR), Peking University, No.5 Yiheyuan Road, Haidian District, Beijing 100871, China.

Briefings in bioinformatics
|March 8, 2026
PubMed
概括

我们开发了scDIAGRAM,这是一种新的方法,可以在单细胞Hi-C (scHi-C) 数据中准确识别A/B区. 这种方法增强了对单细胞水平3D基因组组织和基因调节的理解.

关键词:
A/B 区间的 A/B 区间.染色质异质性的不同一个单细胞的Hi-C.统计建模 统计建模

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