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Updated: Mar 11, 2026

Utilizing In Vivo Postnatal Electroporation to Study Cerebellar Granule Neuron Morphology and Synapse Development
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普尔金尼细胞的内在活动塑造小脑发育和功能.

Catarina Osório1, Joshua J White2, Paula Torrents-Solé2

  • 1Department of Neuroscience, Erasmus Medical Center, Rotterdam, The Netherlands. c.osorio@erasmusmc.nl.

Nature communications
|March 10, 2026
PubMed
概括

普尔金耶细胞的内在活动对于小脑电路的发展至关重要,调节树突细胞的生长和功能. 早期破坏这种功能会损害运动技能,并导致长期的细胞缺陷.

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Cerebellum: Anatomical Regions01:17

Cerebellum: Anatomical Regions

The cerebellum, also known as the "little brain," is located in the posterior cranial fossa, inferior to the tentorium cerebelli and dorsal to the brainstem. It plays a significant role in motor control, coordination, and proprioception.
Cerebellar Structure
Externally, the cerebellum features a highly convoluted surface with numerous folia (narrow ridges) separated by shallow sulci (grooves). The cerebellum is divided into two hemispheres by a thin median structure known as the vermis. The...
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